Navigating clinical pipeline decisions means balancing science, business, and risk. Leaders from biotech and pharma share how robust analysis, adaptability, and cross-functional teamwork drive portfolio success. Aligning scientific rigor with commercial reality is key to advancing programs and achieving better patient outcomes.

Clinical trials succeed when the patient perspective is central. As Lisa Lea notes, “Nothing about us, without us.” Meaningful engagement improves recruitment, retention, and data quality, while reducing costly amendments. Early and ongoing patient input—through advocacy partnerships and transparent feedback—ensures studies are relevant, efficient, and truly serve those they aim to help.

In today’s fast-paced clinical trials, AI is transforming operations. Paulius Ojeras shares how “agentic AI” moves beyond automation, acting as a digital teammate to boost quality, reduce errors, and streamline workflows. Success depends on thoughtful adoption, strong oversight, and investing in team AI literacy.